2. Signaling Pathways
  3. GPCR/G Protein
  4. RGS Protein
  5. RGS Protein Isoform

RGS Protein

 

RGS Protein Related Products (4):

Cat. No. Product Name Effect Purity
  • HY-114865
    BMS-192364
    		Agonist 99.01%
    BMS-192364 is targeting the Gα-RGS interaction to produce an inactive Gα-RGS complex. BMS-192364 reduces urinary bladder contraction and exert RGS-agonist properties by increasing the action of GAPs on Gq proteins. BMS-192364 inhibits calcium flux.
  • HY-70075
    CCG-63808
    		Inhibitor ≥98.0%
    CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.
  • HY-171251
    RGS10 modulator-1
    		Modulator
    RGS10 modulator-1 (compound 15) is a potent RGS10 modulator. RGS10 modulator-1 significantly reverses IFNγ-induced RGS10 protein and mRNA expression. RGS10 modulator-1 reverse the IFNγ-induced COX-2 mRNA and iNOS expression.
  • HY-13509R
    CCG-50014 (Standard)
    		Inhibitor
    CCG-50014 (Standard) is the analytical standard of CCG-50014. This product is intended for research and analytical applications. CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test.